Proton pump inhibitors now safe with plavix?

In the research, published in February 2009 there was concern that on Proton pump inhibitors taking plavix (Clopidogrel) could inhibit worked as plavix in the body. However, in a new study, researchers say that it now safe to take EPI if plavix.
"This is reassuring that there is no clinically significant interaction between Clopidogrel and EPI data", Dr. Deepak Bhatt, announced lead researcher to head which adds cardiology at the Veterans Affairs Boston Healthcare System.Er: "this is in contrast to earlier observations, not randomised studies that showed that if Clopidogrel and a PPI you took it blunted the ability of clopidogrel, to protect from things like heart attack."
The study spanned six months also specified that hatte.Magen bleeding patients that reduces PPI's together with plavix stomach bleeding can be a major complication of taking prescription blood thinners. Doctors often prescribe the two drugs in combination, to prevent blood clotting and to reduce the risk of stomach bleeding.
For the study, Bhatt and colleagues 3,873 patients plavix plavix alone or in combination with omeprazole (Prilosec) or a placebo; randomly assigned Patients received also aspirin.
Over six months had 51 patients stomach bleeding. The researchers found a rate of haemorrhage of 1.1 per cent below those of plavix plus Prilosec and 2.9 percent below those of plavix and a placebo. Furthermore, 109 patients had a heart attack, stroke, died or cardiac procedure takes another.It was these events 4.9% lower than those receiving Prilosec and 5.7 per cent under which receive a placebo
This means that anyone on plavix can start taking PPIs with worry? maybe, perhaps nicht.Die researchers said the study was not completed.You said, the number of participants in the study early selected.Press stopped by the loss of funding was not large enough to allow, a clinically significant difference in the heart cycle events exclude such as heart attack, due to the use of PPIs for the study said.However, the researchers say the study significant increases in the detected the risk of cardiovascular events in participants were considered high risk.
The study commented Professor of cardiology at the University of California, Los Angeles, Dr. Gregg Fonarow said that "there has been considerable concern the patients might interfere with functional testing, Proton pump inhibitors like Prilosec increase based on observational studies and platelets the antiplatelet effects of clopidogrel, cardiovascular events would have."
"" This study is very reassuring, with no signal of cardiovascular heart damage on Proton pump inhibitors, aspirin, Clopidogrel patients are ", said Fonarow involved with the study."Preventive use of Proton pump inhibitors may be appropriate in patients with increased risk for stomach bleeding."
Another expert, Dr. James Brophy, Professor of medicine and epidemiology at the Royal Victoria Hospital in Montreal, said that "much of the problem of previous research in this field observations and potential biases therefore was subject."This latest Feststellung--coupled with the fact that other new studies proposed an increase in cardiac side effects not confirmed-previous studies - is reassuring, he said.
A Danish study found that was together safe plavix and a PPI and interfere with the effects of plavix.
Also the new findings in this study it is still very important to the upstream and disadvantages which combination these or any other medication with your doctor to besprechen.Jeder patient is different and every situation with your doctor discuss matter anders.Diese helps you come up with a treatment that is best for you.
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